Heart metabolism disease claims millions of lives worldwide, with high homocysteine levels and chronic inflammation being significant contributors. Numerous studies suggest that the molecule Trimethylglycine (TMG) is linked to heart health and maintaining healthy homocysteine levels supports optimal cardiovascular function.
Interestingly COQ10, Trimethylglycine has been recognized as a heart-healthy amino acid since the 1950s, but it is still not as well-known compared to the exaggerated supplements in the market.
Recently, I wrote a story about MTHFR polymorphism or mutation: getting checked to prevent cardiovascular issues. Insightful readers who view one of the methylation donors as TMG have requested to introduce this important molecule and how to safely benefit from it through food or supplementation.
In response to their request, I was able to create this concise article using simple language and grant authority to explore this molecule further through reputable sources I reference, discussing the potential use of this nutrient with medical consultants.
First Encounter with TMG Supplements
I was introduced to the remarkable effects of TMG at a scientific conference of experimental scientists in 2005. My lifelong friend Steve effectively bridged the gap between theory and practice by combining rigorous scientific evidence with his personal experience as a biohacker. Using attractive charts displaying data from his biomarkers made it more approachable and appealing for complex subjects.
He emphasized the major causes of "hyperhomocysteinemia," including genetic defects, deficiencies in B vitamins (folate, vitamin B6, B12), renal failure, and interference with homocysteine metabolism due to drugs or metabolic abnormalities .